Somatosensory restoration and neural control strategies in lower-limb prostheses

People with lower-limb amputation cannot directly control or receive feedback from existing prostheses, but emerging technologies aim to address this gap. Some approaches focus on restoring somatosensation in the missing limb, while others record signals from residual muscles for prosthetic control. This review provides an overview of the current state of neuroprosthetics for somatosensory restoration and prosthetic control in lower-limb amputation, offering perspectives on integrating these technologies for bidirectional neuroprostheses.

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Publication Details

Journal
npj Biomedical Innovations.
Published
2025-12-02
DOI
https://doi.org/10.1038/s44385-025-00050-w
Primary Topic
Muscle activation and electromyography studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Somatosensory restoration and neural control strategies in lower-limb prostheses

Lee E. Fisher, He Huang, Brendan Driscoll, Dulce M. Mariscal
npj Biomedical Innovations.
Muscle activation and electromyography studies
article

Somatosensory restoration and neural control strategies in lower-limb prostheses

Lee E. Fisher, He Huang, Brendan Driscoll, Dulce M. Mariscal
article en

Abstract

People with lower-limb amputation cannot directly control or receive feedback from existing prostheses, but emerging technologies aim to address this gap. Some approaches focus on restoring somatosensation in the missing limb, while others record signals from residual muscles for prosthetic control. This review provides an overview of the current state of neuroprosthetics for somatosensory restoration and prosthetic control in lower-limb amputation, offering perspectives on integrating these technologies for bidirectional neuroprostheses.

npj Biomedical Innovations.Vol. 2(1)
University of North Carolina at Chapel Hill (US), North Carolina State University (US), University of Pittsburgh (US), Center for the Neural Basis of Cognition (US), UNC/NCSU Joint Department of Biomedical Engineering (US), Carnegie Mellon University (US)
National Science Foundation, National Institutes of Health
Openalex Percentile: Top 63%
Muscle activation and electromyography studies
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