The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans

These results indicated that RA protected C. elegans from PA14 infection via its antioxidant properties and its ability to improve mitochondrial function, highlighting its potential as a natural compound for addressing PA14 contamination.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-12-02
DOI
https://doi.org/10.3389/fphar.2025.1701885
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
0.00

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article

The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans

Man Qu, Chang Shu, Chunwu Wang, Shunlin Gu et al.
Frontiers in Pharmacology
Genetics, Aging, and Longevity in Model Organisms
article

The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans

Man Qu, Chang Shu, Chunwu Wang, Shunlin Gu, Zhuohang Li, Shihui Nie, Fenglun Zhang, Ying Zhang, Lei Fu, Qijiang Xu, Baojun Shi, Mingjie Fan
article en

Abstract

These results indicated that RA protected C. elegans from PA14 infection via its antioxidant properties and its ability to improve mitochondrial function, highlighting its potential as a natural compound for addressing PA14 contamination.

Frontiers in PharmacologyVol. 16
Nanjing University of Chinese Medicine (CN), Xinjiang Agricultural University (CN), Xinjiang Academy of Agricultural Sciences (CN), Kashi University (CN), Yangzhou University (CN)
National Key Research and Development Program of China
Openalex Percentile: Top 66%
Genetics, Aging, and Longevity in Model Organisms
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