VEXAS syndrome in rheumatology practice: features from a multicenter cohort in north-east Italy
This study underscores the need for a phenotype-driven diagnostic approach to facilitate earlier identification of VEXAS syndrome. Our findings suggest that current estimates of prevalence in rheumatology settings may significantly underestimate the true disease burden. Improved awareness and interdisciplinary collaboration, particularly among rheumatologists, hematologists, and dermatologists, are essential to enhance recognition, diagnosis, and comprehensive care for individuals affected by this complex syndrome.
Authors
- Roberto Padoan (ORCID: https://orcid.org/0000-0002-2356-375X)
- Giovanni Orsolini (ORCID: https://orcid.org/0000-0003-4119-3016)
- Bernd Raffeiner (ORCID: https://orcid.org/0000-0001-6930-7260)
- Paolo Sfriso (ORCID: https://orcid.org/0000-0001-6432-7174)
- Sara Bindoli (ORCID: https://orcid.org/0000-0002-9409-3329)
- Sara Lombardi
- Andrea Doria (ORCID: https://orcid.org/0000-0003-0548-4983)
- Federica Maiolini
- Roberta Ramonda (ORCID: https://orcid.org/0000-0002-9683-8873)
- Riccardo Bixio (ORCID: https://orcid.org/0000-0001-9335-3371)
- Luca Iorio (ORCID: https://orcid.org/0009-0000-2388-7001)
- Irina Guidea
- Sandra Lombardi
- Marta Favero
- Cristina Bernardi
- Greta Morello-Pasin
Institutions
- University of Verona (IT)
- AOL (United States) (US)
- Girls Incorporated (US)
- University of Padua (IT)
- Istituto di Sociologia Internazionale di Gorizia (IT)
- Ospedale di Bolzano (IT)
- Ospedale Sacro Cuore Don Calabria (IT)
- Ospedale San Paolo (IT)
- Ca' Foncello Hospital (IT)
- Azienda Ospedale - Università Padova (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1700737
- Primary Topic
- Otitis Media and Relapsing Polychondritis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Padova