Unveiling the prognostic and immunological role of IFI44 in glioma
IFI44 may drive glioma progression through dual mechanisms of immune microenvironment remodeling and promotion of tumor cell aggressiveness, supporting its potential as a prognostic biomarker and therapeutic target. Although preliminary knockdown and overexpression assays were performed, the underlying mechanisms of IFI44-mediated immune regulation and tumor progression require further investigation.
Authors
- Tingting Tang (ORCID: https://orcid.org/0000-0002-1670-7452)
- Die Jin
- Yanke Wu
- Zekai Song
- Erhu Yan (ORCID: https://orcid.org/0000-0003-4545-7920)
- Lei Mao (ORCID: https://orcid.org/0000-0002-8857-621X)
Institutions
- Wenzhou Medical University (CN)
- Ruian People's Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1080/07853890.2025.2593209
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00