Recognition of <i>Porphyromonas gingivalis</i> lipopolysaccharide by human caspase−4 depends on lipopolysaccharide purity and guanylate-binding protein 1
CASP4 activation depends on PgLPS purity and host cell priming. GBP1 contributes to PgLPS sensing, and OMVs serve as vehicles for PgLPS delivery to the cytosol.
Authors
- Mariko Hanaoka
- Takeshi Into (ORCID: https://orcid.org/0000-0001-9411-9480)
- Eisuke Domae (ORCID: https://orcid.org/0000-0001-5493-7980)
- Taiki Mori (ORCID: https://orcid.org/0000-0003-2941-8497)
Institutions
- Asahi University (JP)
- Biology of Infection (FR)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1080/20002297.2025.2589652
- Citations
- 1
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.80