Comparison of CT-perfusion software packages and validation with true infarct core in patients with acute ischemic stroke

Our findings reveal marked variability in core volume estimates across different CTP software solutions. CMN and syngo.via B provided good accuracy, but performance declined with larger infarcts. Awareness of these discrepancies is critical for clinicians interpreting perfusion maps to optimize AIS treatment decisions and avoid misclassification of patients who might still benefit from reperfusion therapy.