Thirty-Day Mortality Associated With Carbapenemase-Producing <i>Enterobacterales</i> Bloodstream Infections at a Referral Hospital in Peru, 2020–2023

CPE BSIs were independently associated with increased 30-day mortality, with KPC-producing <i>K pneumoniae</i> posing the greatest risk. Despite the predominance of New Delhi Metallo-β-Lactamase (NDM) in our setting, these findings emphasize the clinical severity associated with different carbapenemase types, and the need to tailor interventions accordingly. Strengthening molecular surveillance and ensuring timely access to effective therapies remain critical priorities in NDM-endemic regions, such as Peru.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-11-26
DOI
https://doi.org/10.1093/ofid/ofaf729
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
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article

Thirty-Day Mortality Associated With Carbapenemase-Producing Enterobacterales Bloodstream Infections at a Referral Hospital in Peru, 2020–2023

Roxana Sandoval‐Ahumada, Giancarlo Pérez‐Lazo, José Ballena‐López, Steev Loyola et al.
Open Forum Infectious Diseases
Antibiotic Resistance in Bacteria
article

Thirty-Day Mortality Associated With Carbapenemase-Producing Enterobacterales Bloodstream Infections at a Referral Hospital in Peru, 2020–2023

Roxana Sandoval‐Ahumada, Giancarlo Pérez‐Lazo, José Ballena‐López, Steev Loyola, Fernando Soto‐Febres, Carlos Tairo-Cerron
article en

Abstract

CPE BSIs were independently associated with increased 30-day mortality, with KPC-producing <i>K pneumoniae</i> posing the greatest risk. Despite the predominance of New Delhi Metallo-β-Lactamase (NDM) in our setting, these findings emphasize the clinical severity associated with different carbapenemase types, and the need to tailor interventions accordingly. Strengthening molecular surveillance and ensuring timely access to effective therapies remain critical priorities in NDM-endemic regions, such as Peru.

Open Forum Infectious DiseasesVol. 12(12)
Universidad Científica del Sur (PE), Hospital Base Guillermo Almenara Irigoyen (PE)
Openalex Percentile: Top 67%
Antibiotic Resistance in Bacteria
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Thirty-Day Mortality Associated With Carbapenemase-Producing <i>Enterobacterales</i> Bloodstream Infections at a Referral Hospital in Peru, 2020–2023 — Roxana Sandoval‐Ahumada, Giancarlo Pérez‐Lazo, et al. · Open Forum Infectious Diseases (2025) | TGRS Research Map | TGRS