A Composite Epigenetic Biomarker of <i>FOXP3</i> / <i>TIGIT</i> Correlates With Regulatory T Cell Numbers in Cord Blood and Is Associated With Subsequent Food Allergy
A composite epigenetic biomarker in cord whole blood correlates with the proportion of nTreg in CBWCs and is strongly associated with the absence of subsequent food allergy.
Authors
- Luba Sominsky (ORCID: https://orcid.org/0000-0002-0674-8824)
- Mimi L.K. Tang (ORCID: https://orcid.org/0000-0002-3839-5293)
- John Molloy (ORCID: https://orcid.org/0000-0002-6935-0418)
- Boris Novakovic (ORCID: https://orcid.org/0000-0002-5623-9008)
- Fiona Collier (ORCID: https://orcid.org/0000-0002-5438-480X)
- Poshmaal Dhar (ORCID: https://orcid.org/0000-0002-2842-007X)
- Peter Vuillermin (ORCID: https://orcid.org/0000-0002-6580-0346)
- Peter D. Sly (ORCID: https://orcid.org/0000-0001-6305-2201)
- Martin O’Hely (ORCID: https://orcid.org/0000-0002-0212-1207)
- Viet Hong Nguyen (ORCID: https://orcid.org/0000-0002-0772-6918)
- Anne‐Louise Ponsonby (ORCID: https://orcid.org/0000-0002-6581-3657)
- Richard Saffery (ORCID: https://orcid.org/0000-0002-9510-4181)
Institutions
- Boston Children's Hospital (US)
- Barwon Health (AU)
- Royal Children's Hospital (AU)
- Children's Medical Research Institute (AU)
- Deakin University (AU)
- The University of Melbourne (AU)
- Pham Ngoc Thach University of Medicine (VN)
- Florey Institute of Neuroscience and Mental Health (AU)
- University of Manchester (GB)
- Children’s Health Queensland Hospital and Health Service (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/cea.70172
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deakin University
- Barwon Health Foundation
- Medical Research Council
- National Health and Medical Research Council