Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness

LA-ART for breastfeeding women experiencing adherence challenges could reduce infant infections. If efficacies and costs are confirmed, LA-ART for NVS women would improve outcomes and be minimally cost-saving; for VS women, LA-ART would be cost-effective in Zimbabwe at costs ≤$84/year.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-11-14
DOI
https://doi.org/10.1093/infdis/jiaf521
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
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article

Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness

Risa M. Hoffman, Anesu Chimwaza, Aadia Rana, Shahin Lockman et al.
The Journal of Infectious Diseases
HIV/AIDS Research and Interventions
article

Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness

Risa M. Hoffman, Anesu Chimwaza, Aadia Rana, Shahin Lockman, Angela Mushavi, Karen Webb, Sophie Desmonde, Clare Flanagan, Caitlin M. Dugdale, Anne M. Neilan, S. Horsfall, Kudakwashe C Takarinda, Andrea Ciaranello, Judith S. Currier, Kenneth A. Freedberg, Sujata E. Tewari, Florence Ebem, Kenneth Masiye, Efison Dhodho
article en

Abstract

LA-ART for breastfeeding women experiencing adherence challenges could reduce infant infections. If efficacies and costs are confirmed, LA-ART for NVS women would improve outcomes and be minimally cost-saving; for VS women, LA-ART would be cost-effective in Zimbabwe at costs ≤$84/year.

The Journal of Infectious DiseasesVol. 233(1)
Brigham and Women's Hospital (US), Massachusetts Department of Public Health (US), Université Toulouse III - Paul Sabatier (FR), Harvard University (US), Inserm (FR), University of California, Los Angeles (US), Ministry of Health and Child Welfare (ZW), AIDS United (US), Harvard University Press (US), University of California System (US), University of Alabama at Birmingham (US), Massachusetts General Hospital (US), Centre de recherche en Epidémiologie et Santé des Populations (FR), Botswana Harvard AIDS Institute Partnership (BW), Training Programs in Epidemiology and Public Health Interventions Network (US), Johns Hopkins University Center for AIDS Research
Openalex Percentile: Top 56%
HIV/AIDS Research and Interventions
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