Pericyte-myofibroblast transition: a novel mechanism in peritoneal fibrosis and the effect of Asiaticoside
Our findings repositioned pericytes as pivotal contributors to PF and proposed ASI as a therapeutic agent against PDGFRβ-driven PMT, which provided a new perspective for antifibrotic strategies.
Authors
- Yun Shan
- Yawei Zheng (ORCID: https://orcid.org/0000-0003-2497-7353)
- Manshu Yu
- Lei Tang (ORCID: https://orcid.org/0000-0003-2132-0540)
- Xiaolin Zhu (ORCID: https://orcid.org/0000-0002-3221-595X)
- Jun Shi (ORCID: https://orcid.org/0000-0002-8095-0422)
- Meixiao Sheng (ORCID: https://orcid.org/0000-0002-9901-1361)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Hua Medicine (China) (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.072
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00