Consolidative Radical Cystectomy Following Neoadjuvant Tislelizumab Plus Gemcitabine and Cisplatin in Clinically Lymph Node–positive Bladder Cancer: A Prospective Study

In this study, we investigated the efficacy of neoadjuvant chemoimmunotherapy in patients with clinically lymph node-positive bladder cancer. We found that the clinical effect of completing three neoadjuvant chemoimmunotherapy sessions combined with consolidative radical cystectomy was relatively good. Our conclusion is that neoadjuvant chemoimmunotherapy combined with consolidative radical cystectomy is safe and effective for patients with clinically positive lymph nodes.

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Publication Details

Journal
European Urology Open Science
Published
2025-12-01
DOI
https://doi.org/10.1016/j.euros.2025.11.004
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Consolidative Radical Cystectomy Following Neoadjuvant Tislelizumab Plus Gemcitabine and Cisplatin in Clinically Lymph Node–positive Bladder Cancer: A Prospective Study

Qiang Lü, Juntao Zhuang, Lingkai Cai, Rongjie Bai et al.
European Urology Open Science
Bladder and Urothelial Cancer Treatments
article

Consolidative Radical Cystectomy Following Neoadjuvant Tislelizumab Plus Gemcitabine and Cisplatin in Clinically Lymph Node–positive Bladder Cancer: A Prospective Study

Qiang Lü, Juntao Zhuang, Lingkai Cai, Rongjie Bai, Xiao Yang, Qiang Cao, Tianshuo Feng, Hao Yu
article en

Abstract

In this study, we investigated the efficacy of neoadjuvant chemoimmunotherapy in patients with clinically lymph node-positive bladder cancer. We found that the clinical effect of completing three neoadjuvant chemoimmunotherapy sessions combined with consolidative radical cystectomy was relatively good. Our conclusion is that neoadjuvant chemoimmunotherapy combined with consolidative radical cystectomy is safe and effective for patients with clinically positive lymph nodes.

European Urology Open ScienceVol. 83
Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 43%
Bladder and Urothelial Cancer Treatments
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