Expression of Concern: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

Following the publication and subsequent correction of this article [1,2], concerns were raised regarding results presented in Figs 2, S4, S6, and S8.Specifically, The Fig 2J Direct WB LRP1 panel appears similar to the Fig S4A LRP1 panel when flipped and rotated, despite being used to represent different conditions. The Fig 2J Direct WB Actin panel appears similar to the Fig S4A Actin panel, despite being used to represent different conditions. The Fig S6C Direct WB LRP1 panel appears similar to the Fig S6D Direct WB JAK2 panel.

Publication Details

Journal
PLoS Biology
Published
2025-12-01
DOI
https://doi.org/10.1371/journal.pbio.3003528
Primary Topic
Regulation of Appetite and Obesity
Type
article
Field-Weighted Citation Impact
0.00
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article

Expression of Concern: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

PLoS Biology
Regulation of Appetite and Obesity
article

Expression of Concern: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

article en

Abstract

Following the publication and subsequent correction of this article [1,2], concerns were raised regarding results presented in Figs 2, S4, S6, and S8.Specifically, The Fig 2J Direct WB LRP1 panel appears similar to the Fig S4A LRP1 panel when flipped and rotated, despite being used to represent different conditions. The Fig 2J Direct WB Actin panel appears similar to the Fig S4A Actin panel, despite being used to represent different conditions. The Fig S6C Direct WB LRP1 panel appears similar to the Fig S6D Direct WB JAK2 panel.

PLoS BiologyVol. 23(12)
Openalex Percentile: Top 61%
Regulation of Appetite and Obesity
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Expression of Concern: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System · PLoS Biology (2025) | TGRS Research Map | TGRS