Infiltration of CXCL9+ macrophages confers a favorable prognosis in breast cancer: Insights from an integrated single-cell RNA and bulk RNA sequencing study
CXCL9 + macrophages could play a significant role in inhibiting breast cancer, and their infiltration into tumor tissues is associated with improved survival in breast cancer patients. Immunotherapy targeting CXCL9 + macrophages hold great potential as a therapeutic strategy.
Authors
- Bin Liang (ORCID: https://orcid.org/0000-0002-6130-8629)
- Siyu Long (ORCID: https://orcid.org/0009-0008-7828-3916)
- Peng Zhou (ORCID: https://orcid.org/0009-0002-8478-6911)
- Zhongping Duan
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1371/journal.pone.0337175
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80