Characteristics of Patients with Vasculitis at a Hospital in Northeastern Mexico

Background: Small vessel vasculitis are inflammatory diseases that causing tissue damage and multi-organ involvement with important kidney disease, expressing as rapidly progressive glomerulonephritis with ANCA positive being one of the most common causes. This study describe the clinical, serological and laboratory characteristics in a patients with vasculitis at a hospital in northeastern Mexico Methods: A descriptive, cross-sectional and retrospective study was conducted on patients with vasculitis. Demographigh, serological (ANCA, C-ANCA, P-ANCA, MPO, PR3, ANA, anti-MBG), clinical and laboratory data were evaluated in patients with corfirmatory biopsy. Disease duration was recorded on weeks and months. Descriptive statistics were applied and normality was assessed using Shapiro-Wilk test. Correlations between selected variables were analysed using Spearman and Pearson coefficients. A p-value <0.05 was considered statitically significant. Results: A cohort of 25 patients with confirmed vasculitis was analyzed. Conclusion: ANCA associated vasculitis, mainly P-ANCA predominated with severe renal involvement and a high frecuency of anemia. Sixteen percent were ANCA negative. General malaise was reported in all patients. No significant correletions were found between clinical or laboratory variables and disease duration