Continuous pressure exacerbates ischemia–reperfusion injury in minipigs through the AKT/eNOS signaling pathway
External mechanical forces exacerbate ischemia-reperfusion injury in pressure ulcers by intensifying oxidative stress, inflammation, and fibrosis, mainly through the activation of the AKT/eNOS pathway.
Authors
- Tao Lin (ORCID: https://orcid.org/0000-0001-8584-7101)
- Yanli Luo (ORCID: https://orcid.org/0000-0003-3606-4658)
- Xiaolin Ma (ORCID: https://orcid.org/0000-0002-5348-3435)
- Xiaorong Yang (ORCID: https://orcid.org/0000-0002-6263-9104)
- Ying Yang (ORCID: https://orcid.org/0000-0002-2502-7053)
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s40001-025-03576-2
- Primary Topic
- Pressure Ulcer Prevention and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00