Lipidomic fingerprints reveal sex-, age-, and disease-dependent differences in the TgF344-AD transgenic rats
Our findings highlight the value of lipidomic in identifying early AD-related lipid alterations, offering a promising avenue for understanding disease mechanisms and advancing biomarker discovery.
Authors
- Elizabeth C. M. de Lange (ORCID: https://orcid.org/0000-0001-8303-1117)
- Richard D. Hartman (ORCID: https://orcid.org/0000-0002-3078-3814)
- Amy C. Harms (ORCID: https://orcid.org/0000-0002-2931-4295)
- Chunyuan Yin (ORCID: https://orcid.org/0000-0002-4017-9389)
- Thomas Hankemeier (ORCID: https://orcid.org/0000-0001-7871-2073)
- Alida S. D. Kindt (ORCID: https://orcid.org/0000-0001-6551-6030)
Institutions
- Leiden University (NL)
- Netherlands Metabolomics Centre (NL)
- Centre for Human Drug Research (NL)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1007/s11306-025-02350-z
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- China Scholarship Council