Body talk: Correlates of gut-immune dysregulation phenotypes in people living with HIV who use methamphetamine
Distinct patterns of microbial translocation, immune activation, inflammation, and metabolism of amino acid precursors distinguished gut-immune phenotypes of PWH reporting injection methamphetamine use and greater internalized stigma. Interventions tailored to PWH who inject methamphetamine or struggle with internalized stigma could optimize HIV-related health outcomes.
Authors
- Savita Pahwa (ORCID: https://orcid.org/0000-0002-4470-4216)
- Samantha E. Dilworth (ORCID: https://orcid.org/0000-0002-5451-5486)
- Torsten B. Neilands (ORCID: https://orcid.org/0000-0001-7936-9123)
- Margaret Roach (ORCID: https://orcid.org/0000-0002-3318-2344)
- Suresh Pallikkuth (ORCID: https://orcid.org/0000-0003-4451-8859)
- Wilson Vincent (ORCID: https://orcid.org/0000-0003-1995-4958)
- Sydney H. Telaak (ORCID: https://orcid.org/0000-0003-1468-299X)
- Adam W. Carrico (ORCID: https://orcid.org/0000-0002-8146-5701)
- Cody Lentz (ORCID: https://orcid.org/0000-0002-4666-6305)
- Gowri Sunder (ORCID: https://orcid.org/0000-0002-6476-0696)
- Robert Paul (ORCID: https://orcid.org/0000-0003-4225-6103)
- Dietmar Fuchs (ORCID: https://orcid.org/0000-0003-1627-9563)
- Annesa Flentje (ORCID: https://orcid.org/0000-0002-1964-4151)
- Peter W. Hunt (ORCID: https://orcid.org/0000-0002-4571-4870)
- Benjamin S. Dominguez (ORCID: https://orcid.org/0009-0009-8613-0140)
Institutions
- University of Miami (US)
- University of California, San Francisco (US)
- Universität Innsbruck (AT)
- Florida International University (US)
- University of Missouri–St. Louis (US)
- Temple University (US)
- Stanford University (US)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.bbih.2025.101156
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00