The relationship between testosterone replacement therapy and incidence of proximal humerus fractures in men: a matched retrospective analysis
In this retrospective matched-cohort study, TRT patients demonstrated an increase in 2-year incidence rates of PHF in men. These findings underscore the need for tailored patient management and provide actionable insights for orthopedic practice. Future studies of prospective design are needed to better address confounding factors, establish causation, and evaluate surgical outcomes in TRT patients.
Authors
- Edward J. Testa (ORCID: https://orcid.org/0000-0002-8693-1396)
- Matthew Quinn
- Alan H. Daniels (ORCID: https://orcid.org/0000-0001-9597-4139)
- Gabriella Avellino
- Manjot Singh (ORCID: https://orcid.org/0000-0003-4524-6226)
- Michel A. Arcand (ORCID: https://orcid.org/0000-0003-0046-879X)
- Joseph Confessore
- P Arcand (ORCID: https://orcid.org/0009-0002-4697-4612)
- Simbarashe J. Peresuh
Institutions
- Providence College (US)
- Brown University (US)
- University Gastroenterology (US)
Publication Details
- Journal
- JSES Reviews Reports and Techniques
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.xrrt.2025.100631
- Primary Topic
- Shoulder Injury and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00