Association of triglyceride-glucose index and atherogenic index of plasma with sarcopenia across different glucose metabolism states: the mediating role of oxidative stress and chronic inflammation
In individuals with normal glucose metabolism, elevated AIP and TyG indices show a positive correlation with the occurrence of sarcopenia, and this relationship is partially mediated by the inflammation and oxidative stress present in the individual. Maintaining optimal glycemic and lipid metabolism is crucial for the primary prevention of sarcopenia and related diseases.
Authors
- Junjie Yao (ORCID: https://orcid.org/0000-0002-2381-706X)
- Jing Xu (ORCID: https://orcid.org/0000-0001-8084-5609)
- Yuanyuan Ji (ORCID: https://orcid.org/0000-0001-5591-000X)
- Huijuan Lou
- Xingquan Wu (ORCID: https://orcid.org/0000-0002-6899-4553)
- Yahui Sun
- Deyu Cong (ORCID: https://orcid.org/0000-0001-6495-8291)
Institutions
- Changchun University of Chinese Medicine (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s40001-025-03550-y
- Citations
- 1
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.29