Clinical Performance of HPV DNA and HPV RNA Assays for the Detection of High-Grade Cervical Lesions
While no statistically significant difference was observed between DNA-xGT and DNA-lGT assays in disease detection rate, the mRNA test showed a significantly lower detection rate when compared to the DNA-xGT assay. Most of the missed infections (8/13) were identified as HPV16 or HPV18.
Authors
- Luciana Girotto Gentil (ORCID: https://orcid.org/0000-0002-1530-6809)
- Kevin E. Nelson
- Danijela Lucic (ORCID: https://orcid.org/0000-0002-7276-489X)
- Klara Abravaya
- Shihai Huang (ORCID: https://orcid.org/0000-0002-7886-7195)
- Richard L. Cullum
- Yan Zhang (ORCID: https://orcid.org/0000-0002-7111-7164)
- Cecilia Schmidt
Institutions
- Abbott (United States) (US)
- Abbott (Chile) (CL)
Publication Details
- Journal
- Journal of Lower Genital Tract Disease
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1097/lgt.0000000000000925
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00