Transcriptome-wide association study identifies key genes in Graves' ophthalmopathy
Our findings highlight the genetic architecture of GO, identifying ZSCAN9 and HLA - DMA as potential causal genes, and underscore the importance of integrating multi-omics data to unravel complex disease mechanisms. Subsequent investigations ought to concentrate on corroborating these results and identifying potential therapeutic targets for GO.
Authors
- Jieqing Yuan
- Lingling Meng (ORCID: https://orcid.org/0009-0001-5516-9888)
- Yuting Chen (ORCID: https://orcid.org/0000-0003-0880-1745)
Institutions
- Zhejiang Chinese Medical University (CN)
- Wenzhou Medical University (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- Experimental Eye Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.exer.2025.110776
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00