Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study

This study provides the first fNIRS-based evidence of characteristic functional network changes and compensatory reorganization in CSM patients. The observed hyperconnectivity between the occipital and prefrontal cortices may reflect neuroplastic responses to visual and chronic sensorimotor deficits, while global integration impairments could underlie clinical disabilities. These quantifiable connectivity signatures offer novel targets for monitoring disease progression and evaluating therapeutic interventions.

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Publication Details

Journal
Acta Neurochirurgica
Published
2025-12-01
DOI
https://doi.org/10.1007/s00701-025-06707-0
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study

Xiang Jin, Yan Huang, Fucai Liu, M. A. Wu et al.
Acta Neurochirurgica
Functional Brain Connectivity Studies
article

Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study

Xiang Jin, Yan Huang, Fucai Liu, M. A. Wu, Hai Gao, Zhao Hui Chen, Qi Zhang
article en

Abstract

This study provides the first fNIRS-based evidence of characteristic functional network changes and compensatory reorganization in CSM patients. The observed hyperconnectivity between the occipital and prefrontal cortices may reflect neuroplastic responses to visual and chronic sensorimotor deficits, while global integration impairments could underlie clinical disabilities. These quantifiable connectivity signatures offer novel targets for monitoring disease progression and evaluating therapeutic interventions.

Acta NeurochirurgicaVol. 167(1)
University of Science and Technology of China (CN), Anhui University of Traditional Chinese Medicine (CN), Hefei First People's Hospital (CN)
Openalex Percentile: Top 62%
Functional Brain Connectivity Studies
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Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study — Xiang Jin, Yan Huang, et al. · Acta Neurochirurgica (2025) | TGRS Research Map | TGRS