Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study
This study provides the first fNIRS-based evidence of characteristic functional network changes and compensatory reorganization in CSM patients. The observed hyperconnectivity between the occipital and prefrontal cortices may reflect neuroplastic responses to visual and chronic sensorimotor deficits, while global integration impairments could underlie clinical disabilities. These quantifiable connectivity signatures offer novel targets for monitoring disease progression and evaluating therapeutic interventions.
Authors
- Xiang Jin
- Yan Huang (ORCID: https://orcid.org/0000-0003-4841-7262)
- Fucai Liu (ORCID: https://orcid.org/0000-0003-1275-0573)
- M. A. Wu
- Hai Gao
- Zhao Hui Chen
- Qi Zhang (ORCID: https://orcid.org/0000-0002-9956-8653)
Institutions
- University of Science and Technology of China (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Hefei First People's Hospital (CN)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1007/s00701-025-06707-0
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00