Pulsed Field Ablation Using a Novel Biphasic Catheter vs Thermal Ablation for Paroxysmal Atrial Fibrillation
The nsPFA exhibited noninferior efficacy and comparable safety to AI-guided RFA while obviating the need for general anesthesia. Furthermore, the study revealed that this ablation technique significantly reduced both total procedure time and left atrial dwelling time. (InsightPFA Trial of the LotosPFA Catheter [InsightPFA]; NCT06014996).
Authors
- Guiyang Li (ORCID: https://orcid.org/0000-0002-2802-5766)
- Qiwei Liao
- Weidong Zhuo
- Xingcai Wan
- Chengming Ma (ORCID: https://orcid.org/0000-0001-6259-4455)
- Lian Chen (ORCID: https://orcid.org/0000-0002-0545-2108)
- Yuegang Wang (ORCID: https://orcid.org/0000-0002-1116-8402)
- Hongtao Liao (ORCID: https://orcid.org/0000-0002-6466-3626)
- Jianwu Zhang (ORCID: https://orcid.org/0000-0002-1223-9065)
- Huimin Chu (ORCID: https://orcid.org/0000-0002-2791-6831)
- Yizhou Xu (ORCID: https://orcid.org/0000-0002-8870-5472)
- Guohua Fu (ORCID: https://orcid.org/0000-0002-7588-9452)
- Sijia Pu (ORCID: https://orcid.org/0000-0002-0584-710X)
- Weidong Lin (ORCID: https://orcid.org/0009-0002-2526-7695)
- Xiaofei Gao (ORCID: https://orcid.org/0000-0003-2799-7421)
- Shiquan Chen (ORCID: https://orcid.org/0000-0003-1025-6950)
- Lihong Huang (ORCID: https://orcid.org/0000-0002-7261-316X)
- Feifan Ouyang (ORCID: https://orcid.org/0000-0001-5292-1758)
- Chuangshi Wang
- Jian Yang (ORCID: https://orcid.org/0000-0002-4163-2309)
- Zhuli Guo
- Wenqing Zhu (ORCID: https://orcid.org/0000-0001-8229-0934)
- Lipu Yu
- Songnan Li (ORCID: https://orcid.org/0000-0002-3139-663X)
- Binhao Wang (ORCID: https://orcid.org/0000-0001-5341-3878)
- Shiyu Dai (ORCID: https://orcid.org/0000-0003-3171-4877)
- Wei Li (ORCID: https://orcid.org/0000-0003-4143-8597)
- Wei Wei (ORCID: https://orcid.org/0000-0001-5149-6542)
- Qiang Li (ORCID: https://orcid.org/0000-0001-8353-374X)
- Yuanjun Sun (ORCID: https://orcid.org/0000-0003-3490-2523)
- Yanbo Chen (ORCID: https://orcid.org/0000-0003-4210-0598)
- Xiaomeng Yin (ORCID: https://orcid.org/0000-0002-1359-7307)
- Yumei Xue (ORCID: https://orcid.org/0000-0001-7354-0014)
- Xinzhong Li (ORCID: https://orcid.org/0000-0001-7447-9315)
- Yang Pang
- Liwei He (ORCID: https://orcid.org/0000-0001-5217-4190)
- Weidong Gao (ORCID: https://orcid.org/0000-0003-1809-5290)
- Sen Yang
- Hai Deng (ORCID: https://orcid.org/0000-0002-3285-441X)
- Shaolong Li (ORCID: https://orcid.org/0009-0001-0780-3469)
- Dong Chang
- Faguang Zhou (ORCID: https://orcid.org/0000-0002-1615-6937)
- Dong Xu
- Chenyang Jiang
- Jialan Lv (ORCID: https://orcid.org/0009-0001-4578-0149)
- Yibo Yu (ORCID: https://orcid.org/0009-0007-0022-9648)
- Chende He
Institutions
- Ningbo University (CN)
- Universität Hamburg (DE)
- Capital Medical University (CN)
- Dalian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fudan University (CN)
- Kunming Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- Westlake University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Lifetech Scientific (China) (CN)
- Nanfang Hospital (CN)
- Weifang People's Hospital (CN)
- Beijing Anzhen Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Guangdong Academy of Medical Sciences (CN)
- Yan'an Hospital Affiliated To Kunming Medical University (CN)
- Jiangmen Central Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Yichang Central People's Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Shaoxing People's Hospital (CN)
- Fu Wai Hospital (CN)
- Southern Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jacc.2025.09.1593
- Citations
- 1
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39