Anatomic-sex interaction effects and prognostic stratification in mucoepidermoid carcinoma of the oral cavity minor salivary glands
Prognosis of oral cavity minor salivary gland MEC is significantly modulated by anatomic-sex interactions. Males exhibited paradoxically reduced mortality risks in Palate_other and Other_oral subsites compared to females. Sex-specific anatomic clustering was observed: males predominantly clustered in the hard palate, whereas females showed predilection for the buccal mucosa/retromolar area and soft palate. A follow-up protocol stratified by anatomic subsites was proposed to optimize clinical surveillance.
Authors
- Haotian Zheng (ORCID: https://orcid.org/0000-0002-0599-5794)
- Lin He (ORCID: https://orcid.org/0000-0002-9643-5222)
- Shuang Zhao (ORCID: https://orcid.org/0000-0002-1943-8542)
- Shuang Zhang (ORCID: https://orcid.org/0000-0001-5570-5954)
- Yue Song (ORCID: https://orcid.org/0009-0002-6488-9956)
- Shuang Pan (ORCID: https://orcid.org/0000-0001-8434-0210)
Institutions
- Harbin Medical University (CN)
- Heilongjiang Provincial Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1007/s12672-025-04212-5
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00