Boric acid and quercetin supplementations alleviated paraquat-induced neurotoxic and irritation effects in human SH-SY5Y cells and in ovo models

BA and Qe, particularly in combination, protect neuronal cells from PQ-induced oxidative and mitochondrial damage by restoring redox balance, stabilizing mitochondria, regulating Ca²⁺ homeostasis and modulating apoptosis and attenuating irritation in the in ovo model. These results suggest that BA and Qe may be promising complementary therapeutics to attenuate neurotoxicity caused by environmental toxins.