Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both

Latent autoimmune diabetes in adults (LADA) is a slowly progressive form of autoimmune diabetes that shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy. This review summarizes LADA's presentation, diagnostic criteria, and management, emphasizing the importance of testing for antibodies early in the course of disease when patients have atypical features of type 2 diabetes.

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Publication Details

Journal
Cleveland Clinic Journal of Medicine
Published
2025-12-01
DOI
https://doi.org/10.3949/ccjm.92a.25069
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both

Michelle D. Lundholm, Keren Zhou
Cleveland Clinic Journal of Medicine
Diabetes and associated disorders
article

Latent autoimmune diabetes in adults: Not type 1, not type 2, a little of both

Michelle D. Lundholm, Keren Zhou
article en

Abstract

Latent autoimmune diabetes in adults (LADA) is a slowly progressive form of autoimmune diabetes that shares features of type 1 and type 2 diabetes, often leading to misdiagnosis and a delay in starting needed insulin therapy. This review summarizes LADA's presentation, diagnostic criteria, and management, emphasizing the importance of testing for antibodies early in the course of disease when patients have atypical features of type 2 diabetes.

Cleveland Clinic Journal of MedicineVol. 92(12)
Cleveland Clinic (US), Cleveland Clinic Lerner College of Medicine (US), Case Western Reserve University (US)
Openalex Percentile: Top 61%
Diabetes and associated disorders
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