Integrated metabolomic and transcriptomic analysis reveals digestive tract adaptations to high altitude in Bayanbulak sheep

Bayanbulak sheep adapt to high-altitude hypoxia and thermal stress through epidermal thickening and synergistic interactions between blood and digestive tract metabolites. These adjustments enhance antioxidant capacity, energy reserves, and immune function, offering a robust model for high-altitude adaptation.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2025-12-01
DOI
https://doi.org/10.3389/fvets.2025.1687858
Primary Topic
High Altitude and Hypoxia
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated metabolomic and transcriptomic analysis reveals digestive tract adaptations to high altitude in Bayanbulak sheep

L. Liu, Bin Chen, Wu-Jun Liu, Xuhui Chen et al.
Frontiers in Veterinary Science
High Altitude and Hypoxia
article

Integrated metabolomic and transcriptomic analysis reveals digestive tract adaptations to high altitude in Bayanbulak sheep

L. Liu, Bin Chen, Wu-Jun Liu, Xuhui Chen, Yaling Yang
article en

Abstract

Bayanbulak sheep adapt to high-altitude hypoxia and thermal stress through epidermal thickening and synergistic interactions between blood and digestive tract metabolites. These adjustments enhance antioxidant capacity, energy reserves, and immune function, offering a robust model for high-altitude adaptation.

Frontiers in Veterinary ScienceVol. 12
Xinjiang Agricultural University (CN)
Openalex Percentile: Top 61%
High Altitude and Hypoxia
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