Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling
Together, these findings highlight a context-dependent role of microbiome-derived factors in shaping cutaneous immunity and underscore the therapeutic potential of restoring AHR signaling to enhance the skin's defense against <i>S. aureus</i>, particularly in inflammatory disorders such as AD.
Authors
- Nicholas Kienzle
- Birgit Sauer (ORCID: https://orcid.org/0000-0003-1503-3000)
- Birgit Schittek (ORCID: https://orcid.org/0000-0003-0081-2001)
- Jule Riebelmann
Institutions
- STZ eyetrial (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1726557
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft