Oxaliplatin and amlodipine combination induced reversible Brugada phenocopy: A case report

In this paper, we analyzed the possible mechanism of oxaliplatin combined with amlodipine induced reversible type 1 BrP, so as to provide clinical reference for the safe medication of chemotherapy patients. At the same time, it is suggested that clinicians should pay attention to the risk of synergistic inhibition of ion channels when chemotherapy drugs are combined with antihypertensive drugs, which provides key clinical evidence for reducing the incidence of cardiovascular complications and optimizing multi-drug combination therapy in cancer patients.