The impact of aging on acute coronary syndromes: an EHR-based analysis

In this consecutive cohort of 6,168 ACS patients, 1,036 (17%) were octo- and nonagenarians. Nonagenarians differ compared to 80+ and 85+ patients. At 30 days, mortality rates were 4% in the 80-84 group, 10% in the 85-89 group (p = < 0.001), and 15% in the nonagenarians (p < 0.001). This all-comer single-center study shows that appropriate selection may be feasible for an invasive strategy in ACS octo and nonagenarians in terms of safety and outcome.

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Publication Details

Journal
Netherlands Heart Journal
Published
2025-12-01
DOI
https://doi.org/10.1007/s12471-025-02003-9
Primary Topic
Cardiovascular Health and Disease Prevention
Type
article
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article

The impact of aging on acute coronary syndromes: an EHR-based analysis

Ton A.C.M. Heestermans, Victor A. Umans, Charlotte E. P. Siegers, Jan van Ramshorst et al.
Netherlands Heart Journal
Cardiovascular Health and Disease Prevention
article

The impact of aging on acute coronary syndromes: an EHR-based analysis

Ton A.C.M. Heestermans, Victor A. Umans, Charlotte E. P. Siegers, Jan van Ramshorst, Maurits T. Dirksen, Olivier Drexhage, Quinten P. Hoogervorst
article en

Abstract

In this consecutive cohort of 6,168 ACS patients, 1,036 (17%) were octo- and nonagenarians. Nonagenarians differ compared to 80+ and 85+ patients. At 30 days, mortality rates were 4% in the 80-84 group, 10% in the 85-89 group (p = < 0.001), and 15% in the nonagenarians (p < 0.001). This all-comer single-center study shows that appropriate selection may be feasible for an invasive strategy in ACS octo and nonagenarians in terms of safety and outcome.

Netherlands Heart JournalVol. 34(1)
Noordwest Ziekenhuisgroep (NL)
Openalex Percentile: Top 45%
Cardiovascular Health and Disease Prevention
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