On the role of cation–DNA interactions in surface-assisted DNA lattice assembly

Surface-assisted DNA lattice assembly is used in the synthesis of functional surfaces and as a model of supramolecular network formation. Here, competitive DNA binding of different cation species is investigated by molecular dynamics simulations and correlated with experiments of surface-assisted DNA origami lattice assembly. The results demonstrate that cation-DNA binding has a strong impact on lattice assembly and order.

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Publication Details

Journal
Nanoscale
Published
2025-12-01
DOI
https://doi.org/10.1039/d5nr03695j
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
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On the role of cation–DNA interactions in surface-assisted DNA lattice assembly

Bhanu Kiran Pothineni, Guido Grundmeier, Satoru Tsushima, Adrian Keller et al.
Nanoscale
Advanced biosensing and bioanalysis techniques
article

On the role of cation–DNA interactions in surface-assisted DNA lattice assembly

Bhanu Kiran Pothineni, Guido Grundmeier, Satoru Tsushima, Adrian Keller, Xiaodan Xu
article en

Abstract

Surface-assisted DNA lattice assembly is used in the synthesis of functional surfaces and as a model of supramolecular network formation. Here, competitive DNA binding of different cation species is investigated by molecular dynamics simulations and correlated with experiments of surface-assisted DNA origami lattice assembly. The results demonstrate that cation-DNA binding has a strong impact on lattice assembly and order.

NanoscaleVol. 18(1)
Paderborn University (DE), Helmholtz-Zentrum Dresden-Rossendorf (DE), The Institute of Energy Economics, Japan (JP)
Openalex Percentile: Top 66%
Advanced biosensing and bioanalysis techniques
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