Contemporary adverse event profile of microsurgery for intracranial unruptured aneurysms in high-volume microsurgical centers: the international PRAEMIUM study

This large international cohort provides contemporary benchmarks for microsurgical treatment of UIAs, emphasizing variability in outcomes based on aneurysm location, morphology, and complexity. The presented granular and quotable adverse event rates support informed patient counseling and individualized risk/benefit assessments in comparable high-volume centers.

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Publication Details

Journal
Neurosurgical FOCUS
Published
2025-12-01
DOI
https://doi.org/10.3171/2025.9.focus25723
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
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article

Contemporary adverse event profile of microsurgery for intracranial unruptured aneurysms in high-volume microsurgical centers: the international PRAEMIUM study

Vesna Malinova, Ondra Petr, Joshua S. Catapano, Francesco Acerbi et al.
Neurosurgical FOCUS
Intracranial Aneurysms: Treatment and Complications
article

Contemporary adverse event profile of microsurgery for intracranial unruptured aneurysms in high-volume microsurgical centers: the international PRAEMIUM study

Vesna Malinova, Ondra Petr, Joshua S. Catapano, Francesco Acerbi, Anthony Wang, Anna Štekláčová, Matthias Gmeiner, Kaiyun Yang, Dino Podlesek, Lorenzo Rinaldo, Pietro Meneghelli, Johannes Goldberg, Amir R. Dehdashti, Victor E. Staartjes, Andreas J Gruber, Pietro Fiaschi, Lachlan R. Evans, Jorn Fierstra, Thomas Petutschnigg, Antonio Di Ieva, Philipp Geiger, Paolo Ferroli, Martina Sebök, Alessandro Olivi, Pasquale Anania, Annamaria Auricchio, Ignazio G. Vetrano, Menno R. Germans, Giuseppe S Lanzino, Carlo Serra, Gianluigi Zona, Luca Regli, Michael K. Morgan, Gabriele Schackert, Alexios A. Adamides, Soliman Oushy, Geoffrey Philip Colby, Ann Mansur, Angelo Musumeci, Claudius Thomé, David Bervini, Dorothée Mielke, Paula Klurfan, Sima Sayyahmelli, Sara Sayyahmelli, Asgeir Store Jakola, Vladimír Beneš, Giuseppe Esposito, Ivan Radovanovic, Giampietro Pinna, Andreas Raabe, Mustafa K. Başkaya, Leonardo Olijnyk, Carmelo Lucio Sturiale, Michael T. Lawton, Veit Rohde, John D. Laidlaw, Nico Stroh-Holly, and Aditya M. Kondajji, Karl J. Friston
article en

Abstract

This large international cohort provides contemporary benchmarks for microsurgical treatment of UIAs, emphasizing variability in outcomes based on aneurysm location, morphology, and complexity. The presented granular and quotable adverse event rates support informed patient counseling and individualized risk/benefit assessments in comparable high-volume centers.

Neurosurgical FOCUSVol. 59(6)
Università Cattolica del Sacro Cuore (IT), University of Verona (IT), The Royal Melbourne Hospital (AU), Barrow Neurological Institute (US), Mayo Clinic (US), University of Wisconsin–Madison (US), University of California, Los Angeles (US), University of Zurich (CH), Toronto Western Hospital (CA), North Shore University Hospital (US), University Hospital of Bern (CH), Sahlgrenska University Hospital (SE), Agostino Gemelli University Polyclinic (IT), University Hospital of Zurich (CH), Central Military Hospital (NL), Universitätsmedizin Göttingen (DE), Kepler Universitätsklinikum (AT), Military University Hospital Prague (CZ), Ospedale Policlinico San Martino (IT), University Hospital Carl Gustav Carus (DE), University Hospital Innsbruck (AT), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), University of Göttingen (DE), Technische Universität Dresden (DE), Macquarie University (AU)
Openalex Percentile: Top 48%
Intracranial Aneurysms: Treatment and Complications
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Contemporary adverse event profile of microsurgery for intracranial unruptured aneurysms in high-volume microsurgical centers: the international PRAEMIUM study — Vesna Malinova, Ondra Petr, et al. · Neurosurgical FOCUS (2025) | TGRS Research Map | TGRS