Hemodynamic effects of small abdominal aortic aneurysm morphologies under resting and exercise conditions

This study investigated how low-intensity exercise affects hemodynamics in small saccular and fusiform abdominal aortic aneurysms (AAAs). Patient-specific CFD simulations were performed under resting and exercise conditions. At rest, saccular AAAs exhibited smaller low-shear, high-oscillatory, and high-activation regions than fusiform AAAs. Exercise eliminated low-shear zones and reduced oscillatory behavior but induced high-shear jets impacting saccular walls, while fusiform AAAs showed more uniform flow. These findings suggest that low-intensity exercise improves adverse hemodynamics and achieves a better balance between shear normalization and wall stress in fusiform AAAs, whereas saccular AAAs may experience localized stress elevation and increased rupture risk.

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Publication Details

Journal
Computer Methods in Biomechanics & Biomedical Engineering
Published
2025-12-01
DOI
https://doi.org/10.1080/10255842.2025.2591876
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
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article

Hemodynamic effects of small abdominal aortic aneurysm morphologies under resting and exercise conditions

Tinghui Zheng, Chengxin Weng, Haoyao Cao, Jie Li et al.
Computer Methods in Biomechanics & Biomedical Engineering
Aortic aneurysm repair treatments
article

Hemodynamic effects of small abdominal aortic aneurysm morphologies under resting and exercise conditions

Tinghui Zheng, Chengxin Weng, Haoyao Cao, Jie Li, Ding Yuan
article en

Abstract

This study investigated how low-intensity exercise affects hemodynamics in small saccular and fusiform abdominal aortic aneurysms (AAAs). Patient-specific CFD simulations were performed under resting and exercise conditions. At rest, saccular AAAs exhibited smaller low-shear, high-oscillatory, and high-activation regions than fusiform AAAs. Exercise eliminated low-shear zones and reduced oscillatory behavior but induced high-shear jets impacting saccular walls, while fusiform AAAs showed more uniform flow. These findings suggest that low-intensity exercise improves adverse hemodynamics and achieves a better balance between shear normalization and wall stress in fusiform AAAs, whereas saccular AAAs may experience localized stress elevation and increased rupture risk.

Computer Methods in Biomechanics & Biomedical Engineering
Sichuan University (CN), West China Hospital of Sichuan University (CN), Yibin University (CN)
Openalex Percentile: Top 44%
Aortic aneurysm repair treatments
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Hemodynamic effects of small abdominal aortic aneurysm morphologies under resting and exercise conditions — Tinghui Zheng, Chengxin Weng, et al. · Computer Methods in Biomechanics & Biomedical Engineering (2025) | TGRS Research Map | TGRS