Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa

Rod degeneration induces molecular changes in the P23H/Gnat2-/- mouse rods that suggest synaptic plasticity and strengthening of rod-rod bipolar cell synaptic transmission in early RP.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-12-01
DOI
https://doi.org/10.1167/iovs.66.15.4
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa

Kristiina M. Huttunen, Marcin Tabaka, Elliot H. Choi, Frans Vinberg et al.
Investigative Ophthalmology & Visual Science
Retinal Development and Disorders
article

Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa

Kristiina M. Huttunen, Marcin Tabaka, Elliot H. Choi, Frans Vinberg, Henri Leinonen, Krzysztof Palczewski, Ahmed B. Montaser, Deepa Mathew, Elias Roihuvuo, Anthi‐Styliani Makiou, Lee Sturgis
article en

Abstract

Rod degeneration induces molecular changes in the P23H/Gnat2-/- mouse rods that suggest synaptic plasticity and strengthening of rod-rod bipolar cell synaptic transmission in early RP.

Investigative Ophthalmology & Visual ScienceVol. 66(15)
University of Eastern Finland (FI), University of California, Irvine (US), University of Utah (US), The California Eye Institute (US), Irvine University (US), Institute of Physical Chemistry (PL), Polish Academy of Sciences (PL)
International Retinal Research Foundation, Research to Prevent Blindness, University of Utah, Mary och Georg C. Ehrnrooths Stiftelse, Päivikki ja Sakari Sohlbergin Säätiö, Emil Aaltosen Säätiö, Sigrid Juséliuksen Säätiö, De Blindas Vänner, Silmä- ja kudospankkisäätiö, Business Finland, National Institutes of Health, University of California, Irvine, National Eye Institute
Openalex Percentile: Top 66%
Retinal Development and Disorders
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Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa — Kristiina M. Huttunen, Marcin Tabaka, et al. · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS