Impact of <scp>ALDH2</scp> genotypes and alcohol consumption on age at first‐ever ischemic stroke: A cohort study in Taiwan
In East Asian men, heavy alcohol consumption among ALDH2*2 carriers is associated with earlier ischemic stroke onset, suggesting a gene-environment interaction. These findings support genotype-informed lifestyle counseling for stroke prevention.
Authors
- Jiunn‐Tay Lee
- Hung‐Yi Chiou (ORCID: https://orcid.org/0000-0002-4545-9697)
- Jiann‐Shing Jeng (ORCID: https://orcid.org/0000-0002-1456-3686)
- Chaur‐Jong Hu (ORCID: https://orcid.org/0000-0002-4900-5967)
- Yueh‐Feng Sung (ORCID: https://orcid.org/0000-0001-5984-9277)
- Giia‐Sheun Peng
Institutions
- National Health Research Institutes (TW)
- Taipei Medical University Hospital (TW)
- Tao Yuan General Hospital (TW)
- National Taiwan University Hospital (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taipei Medical University (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/acer.70217
- Citations
- 1
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Academia Sinica
- Tri-Service General Hospital
- Taipei Veterans General Hospital