Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase

Construction of a molecular assembler from DNA that executes a programmed sequence of chemical reactions is a formidable challenge but worthwhile because it would allow assembly and evolution of functional polymers. We present a mechanism using parallel DNA and a DNA polymerase to address two challenges that currently block progress.

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Publication Details

Journal
Nanoscale Horizons
Published
2025-12-01
DOI
https://doi.org/10.1039/d5nh00505a
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase

Andrew J. Turberfield, Jonathan Bath
Nanoscale Horizons
Advanced biosensing and bioanalysis techniques
article

Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase

Andrew J. Turberfield, Jonathan Bath
article en

Abstract

Construction of a molecular assembler from DNA that executes a programmed sequence of chemical reactions is a formidable challenge but worthwhile because it would allow assembly and evolution of functional polymers. We present a mechanism using parallel DNA and a DNA polymerase to address two challenges that currently block progress.

Nanoscale HorizonsVol. 11(2)
University of Oxford (GB)
UK Research and Innovation
Openalex Percentile: Top 66%
Advanced biosensing and bioanalysis techniques
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Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase — Andrew J. Turberfield, Jonathan Bath · Nanoscale Horizons (2025) | TGRS Research Map | TGRS