Multi-Omics Association Analysis of Mitochondrial Genes in Hypertrophic Scars: Application of Mendelian Randomization
This study identified 21 mitochondrial genes with therapeutic potential, with <i>HTATIP2</i> and <i>PDK1</i> being the most promising genes for clinical application, which may strengthen the understanding of HS pathophysiology.
Authors
- Zhaohong Chen (ORCID: https://orcid.org/0000-0003-0050-1924)
- Minjuan Wu (ORCID: https://orcid.org/0009-0009-0350-9981)
- Jiansheng Zheng
- Teng Gong (ORCID: https://orcid.org/0000-0003-1110-2718)
Institutions
- Fujian Medical University (CN)
- Shanghai Medical College of Fudan University (CN)
- 174th hospital of the People's Liberation Army (CN)
- 175th Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jir.s567534
- Citations
- 1
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province