Higher discontinuation with dual orexin receptor antagonists than with benzodiazepines: A Japanese claims cohort study

Dual orexin receptor antagonists are more likely to be discontinued than benzodiazepines after continuous hypnotic prescription, highlighting their potential clinical utility in insomnia treatment.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences
Published
2025-12-01
DOI
https://doi.org/10.1111/pcn.70004
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Higher discontinuation with dual orexin receptor antagonists than with benzodiazepines: A Japanese claims cohort study

Kentaro Matsui, Akiyoshi Shimura, Yoshikazu Takaesu, Yuichi Inoue et al.
Psychiatry and Clinical Neurosciences
Sleep and Wakefulness Research
article

Higher discontinuation with dual orexin receptor antagonists than with benzodiazepines: A Japanese claims cohort study

Kentaro Matsui, Akiyoshi Shimura, Yoshikazu Takaesu, Yuichi Inoue, Kazuhiro Kurihara, Shunsuke Takagi, Ko Sugiura
article en

Abstract

Dual orexin receptor antagonists are more likely to be discontinued than benzodiazepines after continuous hypnotic prescription, highlighting their potential clinical utility in insomnia treatment.

Psychiatry and Clinical NeurosciencesVol. 80(3)
HOGENT University of Applied Sciences and Arts (BE), Tokyo Medical University (JP), Ghent University (BE), University of the Ryukyus (JP), National Center of Neurology and Psychiatry (JP), Institute of Behavioral Sciences (JP), National Institute of Mental Health (JP)
Openalex Percentile: Top 62%
Sleep and Wakefulness Research
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Higher discontinuation with dual orexin receptor antagonists than with benzodiazepines: A Japanese claims cohort study — Kentaro Matsui, Akiyoshi Shimura, et al. · Psychiatry and Clinical Neurosciences (2025) | TGRS Research Map | TGRS