Impact of type 2 diabetes on the relationship between chronic kidney disease and cardiovascular outcomes in heart failure across ejection fraction: observational study from the Swedish heart failure and the Swedish National diabetes registries
In a contemporary HF cohort, decreased kidney function was associated with a progressively higher risk of HHF/CV death, and T2D was not a risk modifier. Renal protection should therefore be implemented in HF regardless of T2D.
Authors
- Soffia Guðbjörnsdóttir (ORCID: https://orcid.org/0000-0002-6583-5581)
- Gianluigi Savarese (ORCID: https://orcid.org/0000-0001-7732-0887)
- Giulia Ferrannini (ORCID: https://orcid.org/0000-0002-0318-7435)
- Christian Basile (ORCID: https://orcid.org/0000-0002-4680-3058)
- Valeria Valente (ORCID: https://orcid.org/0000-0002-7858-5550)
- Lina Benson (ORCID: https://orcid.org/0000-0002-5393-0055)
- Francesco Cosentino (ORCID: https://orcid.org/0000-0002-6967-5685)
- Ulf Dahlström (ORCID: https://orcid.org/0000-0001-6353-8041)
- Lars H. Lund
- Patrizia Rovere-Querini
- Aurora Merolla
Institutions
- Linköping University (SE)
- Karolinska University Hospital (SE)
- Vita-Salute San Raffaele University (IT)
- Karolinska Institutet (SE)
- Stockholm South General Hospital (SE)
- Centre of Registers Vastra Gotaland (SE)
- Södertälje Sjukhus (SE)
- Linköping University Hospital (SE)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Gothenburg (SE)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s12933-025-02998-w
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00