Birth weight and neonatal morbidity as early-life risk factors for childhood cancer: a nationwide cohort study
These findings demonstrate that both birth weight extremes and neonatal exposures contribute to childhood cancer risk. In particular, conditions such as bronchopulmonary dysplasia and sepsis-and interventions including oxygen therapy and transfusions-may influence oncogenic pathways in LBW infants. Long-term follow-up in high-risk neonatal populations is warranted, along with further research into underlying biological mechanisms.
Authors
- In Gyu Song (ORCID: https://orcid.org/0000-0002-3205-9942)
- Yoon-Min Cho (ORCID: https://orcid.org/0000-0002-6970-938X)
- Youna Lim
- Han‐Suk Kim (ORCID: https://orcid.org/0000-0002-9777-3231)
- Euiseok Jung (ORCID: https://orcid.org/0000-0003-0693-5627)
- Seung Han Shin (ORCID: https://orcid.org/0000-0002-1469-589X)
Institutions
- Ulsan College (KR)
- Yonsei University (KR)
- Severance Hospital (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Seoul National University Children's Hospital (KR)
- Korea Institute for Health and Social Affairs (KR)
- National Health Insurance Service (KR)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s12887-025-06382-1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00