Effects of Staphylococcus aureus on Lung Cancer Cells
This study demonstrates that <i>S. aureus</i> infection induces cell-type-specific responses in lung epithelial cells. BEAS-2B cells were more susceptible to colonization, while A549 cells exhibited increased migration and G2/M phase arrest, along with changes in gene expression associated with key cellular pathways. These findings suggest that <i>S. aureus</i> may contribute to pathological processes such as chronic infection or tumor progression at the cellular level.
Authors
- Günel Mukhtarova (ORCID: https://orcid.org/0000-0003-3374-9272)
- Ayşe Caner (ORCID: https://orcid.org/0000-0003-3058-9971)
- Gökhan Gurur Gökmen (ORCID: https://orcid.org/0000-0002-1180-0682)
- Tuncay Göksel (ORCID: https://orcid.org/0000-0002-6089-1840)
- Ufuk Mert (ORCID: https://orcid.org/0000-0001-8162-5325)
- Can Muftuoglu
- Deniz Ece
- Uygar Alaman
- Cagla Ozdenizer
Institutions
- Ege University (TR)
Publication Details
- Journal
- Thoracic research and practice
- Published
- 2025-12-01
- DOI
- https://doi.org/10.4274/thoracrespract.2025.s009
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ege Üniversitesi