Expression Profile of circRNA in Lung Cancer Cells Infected with Staphylococcus aureus

In this study, <i>S. aureus</i> infection A549 lung cancer and BEAS-2B normal bronchial epithelial cells were successfully achieved and the effects of infection on the circRNA expression profile were evaluated. The data obtained show that infection changes the expression of hsa_circ_0000003, hsa_circ_0043278, hsa_circ_0005320, hsa_circ_0001421, hsa_circ_0003998, hsa_circ_0056285, hsa_circ_0001821, hsa_circ_0077837 and hsa_circ_0000326 CIRCRNA in host cells, and that these molecules can undertake potential regulatory roles in the infection response. These different expressions in the infection process of circRNA can both contribute to a better understanding of disease mechanisms and can be considered as biomarker or therapeutic target in the future.