Repeatability and reproducibility of maximum diameter measurements of prostate lesions on MRI with repositioning and variation of imaging sequences: A test-retest study
Prostate lesion measurements demonstrate considerable variability. When measured in one reading session by one rater, lesion diameter differences below the pooled RCs of 4.8 mm, 95 %-CI [3.9, 5.6] for T2WI and 5.8 mm, 95 %-CI [4.7, 7.1] for DWI should not necessarily assumed to be true biological change, as these differences may result from measurement- or repositioning-based variability alone. Caution needs to be taken assessing size changes.
Authors
- Magdalena Görtz (ORCID: https://orcid.org/0000-0001-6195-1609)
- Kevin Sun Zhang (ORCID: https://orcid.org/0000-0003-4044-109X)
- David Bonekamp (ORCID: https://orcid.org/0000-0002-4811-0087)
- Albrecht Stenzinger (ORCID: https://orcid.org/0000-0003-1001-103X)
- Nils Netzer (ORCID: https://orcid.org/0000-0001-5805-0535)
- Vivienn Weru (ORCID: https://orcid.org/0000-0002-7509-3307)
- Markus Hohenfellner (ORCID: https://orcid.org/0000-0003-3798-2039)
- Thomas Hielscher (ORCID: https://orcid.org/0000-0003-1277-310X)
- Markus Wennmann (ORCID: https://orcid.org/0000-0002-8092-8380)
- Lukas T. Rotkopf (ORCID: https://orcid.org/0000-0001-9862-218X)
- Clara Meinzer
- Christian Jan Oliver Neelsen
- Philip Glemser
- H Schlemmer
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- National Center for Tumor Diseases (DE)
Publication Details
- Journal
- Magnetic Resonance Imaging
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.mri.2025.110578
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00