Down-regulation of ACSM3 Promotes Tumorigenesis in Breast Cancer

ACSM3 functions as a tumor suppressor in breast cancer by regulating the WNT/AKT signaling pathway, thereby inhibiting cell proliferation, migration, and invasion. These results suggest that ACSM3 may serve as a potential therapeutic target for breast cancer treatment.

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Publication Details

Journal
Anticancer Research
Published
2025-11-29
DOI
https://doi.org/10.21873/anticanres.17879
Primary Topic
Wnt/β-catenin signaling in development and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Down-regulation of ACSM3 Promotes Tumorigenesis in Breast Cancer

Hong-Beum Kim, Seong‐Hun Kim, Hee-Jeong Lee, Sang-Gon Park
Anticancer Research
Wnt/β-catenin signaling in development and cancer
article

Down-regulation of ACSM3 Promotes Tumorigenesis in Breast Cancer

Hong-Beum Kim, Seong‐Hun Kim, Hee-Jeong Lee, Sang-Gon Park
article en

Abstract

ACSM3 functions as a tumor suppressor in breast cancer by regulating the WNT/AKT signaling pathway, thereby inhibiting cell proliferation, migration, and invasion. These results suggest that ACSM3 may serve as a potential therapeutic target for breast cancer treatment.

Anticancer ResearchVol. 45(12)
Chosun University (KR), Chosun University Hospital (KR)
Openalex Percentile: Top 66%
Wnt/β-catenin signaling in development and cancer
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