Shenlian-Fumai formula attenuates ventricular arrhythmias via modulating sodium channel function in heart failure mice
SLFM exhibits antiarrhythmic and cardioprotective effects in HF by regulating sodium channel function and CaMKII signaling, highlighting its potential as a therapeutic option for HF-related VAs. However, all data were obtained from a single batch of SLFM, limiting generalizability and requiring validation with additional batches and harvest years.
Authors
- Junyan Xia (ORCID: https://orcid.org/0000-0001-7899-2175)
- Tianshi Mao (ORCID: https://orcid.org/0000-0003-4676-7584)
- Bai-Ru Cheng
- Qun Gao (ORCID: https://orcid.org/0000-0002-4940-3092)
- Ruli Feng
- Long Xie (ORCID: https://orcid.org/0000-0002-4016-8655)
- Yun Cai (ORCID: https://orcid.org/0000-0001-6687-9984)
- Yi Pan (ORCID: https://orcid.org/0000-0001-8697-6714)
- Qian Lin (ORCID: https://orcid.org/0000-0001-9166-5099)
- Kaixin Jiang
- Xinyan Qu
Institutions
- Jining Traditional Chinese Medicine Hospital (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
- China Academy of Chinese Medical Sciences (CN)
- Shandong Academy of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.jep.2025.120972
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00