Optimal Duration of Hydrodistension for Symptomatic Treatment of Interstitial Cystitis: A Systematic Review

HD remains a contentious treatment option for IC, with limited long-term results in the literature. Our study suggests longer HD times may result in improved efficacy and duration of symptom relief but in the setting of potentially increased risks of severe complications including bladder perforation. Risk of bias, observational study designs, heterogeneity, and lack direct comparisons in durations of HD limits our conclusions. This review underscores the need for larger, prospective trials determining the effects of HD duration on treatment efficacy.

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Publication Details

Journal
Neurourology and Urodynamics
Published
2025-11-29
DOI
https://doi.org/10.1002/nau.70190
Primary Topic
Urinary Bladder and Prostate Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimal Duration of Hydrodistension for Symptomatic Treatment of Interstitial Cystitis: A Systematic Review

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Neurourology and Urodynamics
Urinary Bladder and Prostate Research
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Optimal Duration of Hydrodistension for Symptomatic Treatment of Interstitial Cystitis: A Systematic Review

Scott Donnellan, Zein Alhamdani, Kirby R. Qin, Paul Manohar, Matthew Harper, Sean Lim, Weranja Ranasinghe, Alexander L. Nesbitt, Janelle Brennan
article en

Abstract

HD remains a contentious treatment option for IC, with limited long-term results in the literature. Our study suggests longer HD times may result in improved efficacy and duration of symptom relief but in the setting of potentially increased risks of severe complications including bladder perforation. Risk of bias, observational study designs, heterogeneity, and lack direct comparisons in durations of HD limits our conclusions. This review underscores the need for larger, prospective trials determining the effects of HD duration on treatment efficacy.

Neurourology and UrodynamicsVol. 45(2)
Monash Health (AU), Bendigo Health (AU), Austin Health (AU), Monash University (AU)
Openalex Percentile: Top 48%
Urinary Bladder and Prostate Research
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