Heat‐Not‐Burn Tobacco Aerosols Induce Immune Dysregulation and Barrier Disruption Comparable to Conventional Cigarettes
Despite different molecular impacts, HnB aerosol exposure induces a level of airway epithelial injury and immune cell infiltration comparable to CC smoke. Our findings challenged the narrative of HnB products being a harmless alternative and highlight their potential to cause significant lung pathology.
Authors
- Karol Adam Kamiński (ORCID: https://orcid.org/0000-0002-9465-2581)
- Natalia Ogrodnik
- Paweł Sowa (ORCID: https://orcid.org/0000-0002-8357-5816)
- Marlena Tynecka (ORCID: https://orcid.org/0000-0002-1693-7549)
- Alicja Walewska (ORCID: https://orcid.org/0000-0003-0610-6191)
- Agnieszka Tarasik (ORCID: https://orcid.org/0009-0005-1655-6219)
- Marlena Dubatówka (ORCID: https://orcid.org/0000-0001-5977-0745)
- Małgorzata Chlabicz (ORCID: https://orcid.org/0000-0002-5113-5672)
- Adam Jacek Kretowski (ORCID: https://orcid.org/0000-0002-4522-4978)
- Kinga Bondarczuk (ORCID: https://orcid.org/0000-0002-9488-1480)
- Dilara Karagüzel (ORCID: https://orcid.org/0000-0001-5986-4311)
- Andrzej Eljaszewicz (ORCID: https://orcid.org/0000-0002-8980-1474)
- Dariusz G. Kisiel (ORCID: https://orcid.org/0009-0000-9779-7586)
- Basak Ezgi Sarac (ORCID: https://orcid.org/0000-0003-1181-4598)
- Marcin Moniuszko (ORCID: https://orcid.org/0000-0001-7183-3120)
- Çağatay Karaaslan (ORCID: https://orcid.org/0000-0003-4857-0857)
- Magdalena Niemira (ORCID: https://orcid.org/0000-0002-0701-4961)
- Damian Pogodziński (ORCID: https://orcid.org/0000-0001-6484-0875)
- Bartosz Hanczaruk (ORCID: https://orcid.org/0009-0003-7070-3553)
- Doga Oztabak (ORCID: https://orcid.org/0009-0007-9404-7844)
- Cagla Bicakci (ORCID: https://orcid.org/0009-0004-7997-6299)
- Alicja Toczydlowska (ORCID: https://orcid.org/0009-0003-5684-6486)
- Karolina Partyk
Institutions
- Medical University of Białystok (PL)
- Hacettepe University (TR)
Publication Details
- Journal
- Allergy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/all.70174
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundacja na rzecz Nauki Polskiej
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- Hacettepe Üniversitesi
- European Regional Development Fund