A Novel Fluorescent Probe for Zn <sup>2+</sup> Detection in Aqueous and Application in Environmental Samples and Cells Bioimaging
A novel salicylaldehyde-benzohydrazide-based fluorescent probe L was designed and synthesized. The probe displayed excellent specificity and sensitivity for Zn<sup>2+</sup> detection in aqueous media (HEPES buffer, pH = 7.40), accompanied by a remarkable colorimetric fluorescence change from colorless to green under a 365 nm UV lamp. The detection mechanism of probe L for Zn<sup>2+</sup> was elucidated by <sup>1</sup>H NMR, HRMS, and DFT calculation. Moreover, the probe was effectively applied in the detection of Zn<sup>2+</sup> in both environmental samples and biological imaging in living cells.
Authors
- Huajie Kong (ORCID: https://orcid.org/0000-0001-8953-3425)
- Xin Hu (ORCID: https://orcid.org/0000-0001-5113-1869)
- Yun Jae Yang (ORCID: https://orcid.org/0000-0003-0993-3096)
- Qiqi Zuo
- Kuoxi Xu (ORCID: https://orcid.org/0000-0002-0081-3621)
- Dandan Li (ORCID: https://orcid.org/0000-0002-3504-8739)
- Mingzhe Li (ORCID: https://orcid.org/0000-0002-3988-8823)
Institutions
- Henan University (CN)
- Zhengzhou University of Light Industry (CN)
Publication Details
- Journal
- Luminescence
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/bio.70373
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00