Electroreduction cross-coupling of thiosulfonates with (hetero)aryl boronic acids to access thioethers
Herein, we present a robust electrochemically driven, 1-iodonaphthalene-enabled cross-coupling of thiosulfonates with arylboronic acids for the synthesis of thioether molecules. This reaction is characterized by exceptional selectivity, gentle reaction conditions, a broad substrate scope, and significant functional group tolerance that extends to late-stage modifications of biologically relevant molecules.
Authors
- Yaqin Zhou (ORCID: https://orcid.org/0000-0003-3788-8122)
- Zhiheng Zhao
- Meimei Chen (ORCID: https://orcid.org/0000-0002-7506-0089)
- Lijun Gu (ORCID: https://orcid.org/0000-0002-8942-0401)
- Chi Zhang (ORCID: https://orcid.org/0000-0002-7422-2584)
- Lei Jiang (ORCID: https://orcid.org/0000-0002-9295-2388)
Institutions
- Guizhou University (CN)
- Zhejiang Medicine (China) (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1039/d5cc05687j
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00