Electroacupuncture pretreatment ameliorates anesthesia and surgery-induced cognitive dysfunction in aged rats: insights from gut microbiota modulation
Electroacupuncture was associated with improved postoperative cognitive function in aged rats after propofol anesthesia and tibial surgery. These effects were accompanied by alterations in gut microbiota composition, suggesting a possible link with the gut-brain axis, although causality remains to be established.
Authors
- Zhendong Ding (ORCID: https://orcid.org/0000-0001-5178-8983)
- Juan Deng (ORCID: https://orcid.org/0000-0002-1811-4183)
- Huajuan Lei
- Huan Lei (ORCID: https://orcid.org/0000-0002-5601-3754)
- Honghui Li (ORCID: https://orcid.org/0000-0001-6113-6831)
- Ziou Li
Institutions
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Xiangtan Electric Manufacturing Group (China) (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fmicb.2025.1642337
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Central South University
- Hunan University
- Xiangya Hospital, Central South University